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Targeted Therapy

Targeted therapy is an advanced form of cancer treatment that focuses on specific molecules involved in the growth, spread, and survival of cancer cells. Unlike chemotherapy, which attacks all rapidly dividing cells, targeted therapy aims to interfere only with cancer-specific genes or proteins, making it a more precise and often less harmful treatment option.

How Targeted Therapy Works

Targeted therapies are designed to block the growth and spread of cancer by acting on particular targets found in cancer cells or the surrounding environment. It works by:

  • Blocking Growth Signals: Interrupting signals that tell cancer cells to grow and divide.
  • Triggering Cell Death: Causing cancer cells to self-destruct without harming healthy cells.
  • Preventing Blood Supply: Inhibiting the formation of new blood vessels that tumors need to grow.
  • Boosting Immune Detection: Helping the immune system better recognize and destroy cancer cells.
  • Types of Targeted Therapy

    There are two main types of targeted therapy, each functioning in a unique way to fight cancer:

    1. Small Molecule Drugs

    These are usually taken orally and enter cells easily to block the activity of proteins that cancer cells need to grow.

    2. Monoclonal Antibodies

    These are lab-made antibodies that bind to specific targets on the surface of cancer cells, blocking their function or marking them for destruction by the immune system.

    How Targeted Therapy is Administered

    Depending on the specific drug and type of cancer, targeted therapy may be given in several ways:

    • Oral Tablets or Capsules
    • Intravenous (IV) Infusion
    • Injection
    • Benefits of Targeted Therapy

      Targeted therapy offers several advantages over traditional cancer treatments:

      • Precision Treatment: Focuses on cancer-specific genes and proteins, minimizing damage to normal cells.
      • Fewer Side Effects: Generally better tolerated than chemotherapy.
      • Effective for Resistant Cancers: Can work when other treatments have failed.
      • Potential Side Effects of Targeted Therapy

        While usually milder than chemotherapy, targeted therapies can still cause side effects, including:

        • Skin Rashes
        • Diarrhea
        • Fatigue
        • Liver Problems
        • Blood Pressure Changes
        • The Future of Targeted Therapy

          Ongoing research is expanding the use of targeted therapies, making treatments more specific, personalized, and effective. Combination approaches with immunotherapy and other treatments are also showing promising results.

          Conclusion

          Targeted therapy represents a major advancement in cancer care by offering more personalized and less toxic treatments. With continued innovation, it holds the potential to transform outcomes for many cancer patients worldwide.